- Abstract:
-
OBJECTIVE: Mouse articular cartilage (AC) is mostly assessed by histopathology and its mechanics is poorly characterised. In this study: (1) we developed non-destructive imaging for quantitative assessment of AC morphology and (2) evaluated the mechanical implications of AC structural changes. METHODS: Knee joints obtained from naïve mice and from mice with osteoarthritis (OA) induced by destabilization of medial meniscus (DMM) for 4 and 12 weeks, were imaged by phosphotungstic acid (PTA) con...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.joca.2014.07.014
-
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- Publisher:
- W.B. Saunders Ltd
- Journal:
- Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society
- Volume:
- 22
- Issue:
- 10
- Pages:
- 1419-1428
- Publication date:
- 2014-10-05
- DOI:
- EISSN:
-
1522-9653
- ISSN:
-
1063-4584
- URN:
-
uuid:a0f81fd1-ffe1-4440-8c4d-9c6e594f525e
- Source identifiers:
-
486192
- Local pid:
- pubs:486192
- Copyright date:
- 2014
Journal article
Rapid, automated imaging of mouse articular cartilage by microCT for early detection of osteoarthritis and finite element modelling of joint mechanics.
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