Thesis
Characterisation of placental and platelet exosome-bound cardiotrophin-1 in cardiomyocyte and endothelial cell function
- Abstract:
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Maternal cardiovascular adaptions during pregnancy have been well described and include characteristic changes in cardiac morphology and function. The mechanisms behind these changes remain largely unknown but are tied to the developing feto-placental unit. Extracellular vesicles are membrane-encapsulated particles carrying cargo originating from their parental cells and are critical mediators of intercellular communication. Syncytiotrophoblast extracellular vesicles (STB-EV), comprising o...
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Authors
Contributors
+ Manu Vatish
Department:
University of Oxford
Role:
Supervisor
+ Ian Sargent
Role:
Supervisor
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Terms of use
- Copyright holder:
- Vuyane Mhlomi
- Copyright date:
- 2017
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