- Abstract:
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BACKGROUND: Genome-wide association studies (GWAS) have identified more than 100 genetic loci for various cancers. However, only one is for endometrial cancer. METHODS: We conducted a three-stage GWAS including 8,492 endometrial cancer cases and 16,596 controls. After analyzing 585,963 single-nucleotide polymorphisms (SNP) in 832 cases and 2,682 controls (stage I) from the Shanghai Endometrial Cancer Genetics Study, we selected the top 106 SNPs for in silico replication among 1,265 cases and ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1158/1055-9965.epi-11-1160
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- Journal:
- Cancer epidemiology, biomarkers and prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
- Volume:
- 21
- Issue:
- 6
- Pages:
- 980-987
- Publication date:
- 2012-06-05
- DOI:
- EISSN:
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1538-7755
- ISSN:
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1055-9965
- URN:
-
uuid:a0eeda67-941d-48a3-83d0-82a13400ee14
- Source identifiers:
-
325160
- Local pid:
- pubs:325160
- Copyright date:
- 2012
Journal article
Genome-wide association study identifies a possible susceptibility locus for endometrial cancer.
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