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Reconstruction of the ancestral metazoan genome reveals an increase in genomic novelty

Abstract:
Many genomic changes took place along the evolutionary lineage that gave rise to the Animal Kingdom. Recent research has revealed the role that co-option of old genes played during this transition, but the contribution of genomic novelty has not been fully assessed. Our analyses of a large genomic dataset using new phylogeneticallyaware tools revealed an increase of genomic novelty in the dawn of the Metazoa not seen before, and highlight 25 groups of highly retained novel genes with functions essential to metazoan biology.
Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Oxford college:
Merton College
Role:
Author
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Name:
Seventh Framework Programme
Grant:
268513
Publisher:
Nature Publishing Group
Journal:
Nature Communications More from this journal
Volume:
9
Pages:
1730
Publication date:
2018-04-30
Acceptance date:
2018-02-28
DOI:
EISSN:
2041-1723
Pubs id:
pubs:833445
UUID:
uuid:a0ec9d87-b027-4850-8707-84992f4f5576
Local pid:
pubs:833445
Source identifiers:
833445
Deposit date:
2018-04-04

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