Regulatory T cells: hypes and limitations.

Journal article

PURPOSE OF REVIEW: In recent years there has been increased interest in understanding the physiology and function of regulatory T cells. In this review we focus on the characterization of regulatory T-cell subsets and their potential therapeutic use in organ transplantation. RECENT FINDINGS: Regulatory T cells can play an instrumental role in the establishment of operational tolerance to allografts. The level of expression and the extent of posttranslational acetylation of the regulatory T-c...

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Authors: Schiopu, A; Wood, K

• Publication status: Published
• Journal: Current opinion in organ transplantation
• Volume: 13
• Issue: 4
• Pages: 333-338
• Publication date: 2008-08-01
• DOI: 10.1097/mot.0b013e3283061137
• EISSN: 1531-7013
• ISSN: 1087-2418
• Language: English
• Keywords: T-Lymphocytes, Regulatory; T-Lymphocyte Subsets; Humans; Transplantation Tolerance; Immunosuppressive Agents; Graft Rejection; Treatment Outcome; Transplantation, Homologous; Animals; Adoptive Transfer; Graft Survival; Organ Transplantation