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Journal article

Normal radial migration and lamination are maintained in dyslexia-susceptibility candidate gene homolog Kiaa0319 knockout mice.

Abstract:

Developmental dyslexia is a common disorder with a strong genetic component, but the underlying molecular mechanisms are still unknown. Several candidate dyslexia susceptibility genes, including KIAA0319, DYX1C1 and DCDC2, have been identified in humans. RNA interference experiments targeting these genes in rat embryos have shown impairments in neuronal migration, suggesting that defects in radial cortical migration could be involved in the disease mechanism of dyslexia. Here we present the f...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1007/s00429-016-1282-1

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Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
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Department:
Oxford, MSD, RDM, RDM Clinical Laboratory Sciences
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Author
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Funding agency for:
Velayos-Baeza, A
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Funding agency for:
Monaco, AP
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Publisher:
Springer Publisher's website
Journal:
Brain Structure & Function Journal website
Publication date:
2016-08-05
Acceptance date:
2016-07-26
DOI:
ISSN:
1863-2661 and 1863-2653
Pubs id:
pubs:638527
URN:
uri:a0d7451c-555c-487f-a748-3c33af76a7a5
UUID:
uuid:a0d7451c-555c-487f-a748-3c33af76a7a5
Local pid:
pubs:638527

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