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Journal article

Involvement of the mannose receptor in infection of macrophages by influenza virus

Abstract:

Influenza viruses A/PR/8/34 (PR8; H1N1), A/Aichi/68 X-31 (HKx31; H3N2), and A/Beijing/89 X-109 (BJx109; H3N2) show marked differences in their ability to infect murine macrophages, including resident alveolar and peritoneal macrophages as well as the macrophage-derived cell line J774. The hierarchy in infectivity of the viruses (PR8 < HKx31 < BJx109) resembles that of their reactivity with mannose-binding lectins of the collectin family. Since the macrophage mannose receptor recognizes ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Publisher:
American Society of Microbiology Publisher's website
Journal:
Journal of Virology Journal website
Volume:
74
Issue:
11
Pages:
5190-5197
Publication date:
2000-06-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
Source identifiers:
274615
Language:
English
Pubs id:
pubs:274615
UUID:
uuid:a0beaa43-ba6f-498c-8690-038e5a028d89
Local pid:
pubs:274615
Deposit date:
2016-03-03

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