Journal article icon

Journal article

Ty virus-like particles, DNA vaccines and Modified Vaccinia Virus Ankara; comparisons and combinations.

Abstract:

Three types of vaccine, all expressing the same antigen from Plasmodium berghei, or a CD8+ T cell epitope from that antigen, were compared for their ability to induce CD8+ T cell responses in mice. Higher levels of lysis and numbers of IFN-gamma secreting T cells were primed with Ty virus-like particles and Modified Vaccinia Virus Ankara (MVA) than with DNA vaccines, but none of the vaccines were able to protect immunised mice from infectious challenge even after repeated doses. However, when...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1515/bc.1999.041

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
Expand authors...
Journal:
Biological chemistry
Volume:
380
Issue:
3
Pages:
299-303
Publication date:
1999-03-01
DOI:
EISSN:
1437-4315
ISSN:
1431-6730
Source identifiers:
31471
Language:
English
Keywords:
Pubs id:
pubs:31471
UUID:
uuid:a0b8968a-3871-462e-a299-be81d8d4f4db
Local pid:
pubs:31471
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP