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Investigation of the actin scavenging system in pre-eclampsia

Abstract:

Objectives Cell injury releases actin, the most abundant cell protein. Gelsolin and vitamin D binding protein (VDBP) together depolymerise and clear cell-free actin. Impaired actin clearance is associated with several diseases and correlates with clinical outcome. The actin scavenging system was investigated in pre-eclampsia (PE), a procoagulant and proinflammatory state with placental and vascular damage. Study design Plasma gelsolin and actin free VDBP (AFVDBP) were measured in PE (early on...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Author
Journal:
EUROPEAN JOURNAL OF OBSTETRICS and GYNECOLOGY AND REPRODUCTIVE BIOLOGY More from this journal
Volume:
172
Issue:
1
Pages:
32-35
Publication date:
2014-01-01
DOI:
EISSN:
1872-7654
ISSN:
0301-2115
Language:
English
Keywords:
Pubs id:
pubs:447245
UUID:
uuid:a0985ec1-3655-4e76-bdd3-0496c6224a14
Local pid:
pubs:447245
Source identifiers:
447245
Deposit date:
2014-12-23

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