- Abstract:
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Background: The control of Clostridium difficile infection is a major international healthcare priority, hindered by a limited understanding of transmission epidemiology for these bacteria. However, transmission studies of bacterial pathogens are rapidly being transformed by the advent of next generation sequencing.
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Results: Here we sequence whole C. difficile genomes from 486 cases arising over four years in Oxfordshire. We show that we can... - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
-
(pdf, 629.8KB)
-
- Publisher copy:
- 10.1186/gb-2012-13-12-r118
-
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- Publisher:
- BioMed Central Publisher's website
- Journal:
- Genome Biology Journal website
- Volume:
- 13
- Issue:
- 12
- Pages:
- R118
- Publication date:
- 2012-12-21
- Acceptance date:
- 2012-12-21
- DOI:
- EISSN:
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1465-6906
- ISSN:
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1474-760X
- Pubs id:
-
pubs:369865
- URN:
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uri:a0826485-207e-4021-a39b-6f2c4e25bb15
- UUID:
-
uuid:a0826485-207e-4021-a39b-6f2c4e25bb15
- Local pid:
- pubs:369865
- Language:
- English
- Keywords:
- Copyright holder:
- Didelot et al.
- Copyright date:
- 2012
- Notes:
- © The Authors 2013; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Microevolutionary analysis of Clostridium difficile genomes to investigate transmission
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Funding
087646/Z/08/Z/Wellcome Trust
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090532/Wellcome Trust
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090532/Z/09/Z/Wellcome Trust
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DRF-2010-03-40/Department of Health
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G0600719B/Medical Research Council
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