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Journal article

Microevolutionary analysis of Clostridium difficile genomes to investigate transmission

Abstract:

Background: The control of Clostridium difficile infection is a major international healthcare priority, hindered by a limited understanding of transmission epidemiology for these bacteria. However, transmission studies of bacterial pathogens are rapidly being transformed by the advent of next generation sequencing.
Results: Here we sequence whole C. difficile genomes from 486 cases arising over four years in Oxfordshire. We show that we can...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
More from this funder
Name:
G0800778/Department of Health
More from this funder
Name:
G0600719B/Medical Research Council
More from this funder
Name:
DRF-2010-03-40/Department of Health
More from this funder
Name:
MR/K010174/1B/Medical Research Council
Publisher:
BioMed Central
Journal:
Genome Biology More from this journal
Volume:
13
Issue:
12
Pages:
R118
Publication date:
2012-12-21
Acceptance date:
2012-12-21
DOI:
EISSN:
1465-6906
ISSN:
1474-760X
Pmid:
23259504
Language:
English
Keywords:
Pubs id:
pubs:369865
UUID:
uuid:a0826485-207e-4021-a39b-6f2c4e25bb15
Local pid:
pubs:369865
Source identifiers:
369865
Deposit date:
2017-08-30

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