Background: The control of Clostridium difficile infection is a major international healthcare priority, hindered by a limited understanding of transmission epidemiology for these bacteria. However, transmission studies of bacterial pathogens are rapidly being transformed by the advent of next generation sequencing.Expand abstract
Results: Here we sequence whole C. difficile genomes from 486 cases arising over four years in Oxfordshire. We show that we can...
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- Didelot et al.
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- © The Authors 2013; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Microevolutionary analysis of Clostridium difficile genomes to investigate transmission
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