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Journal article

Sequence-specific synthesis of macromolecules using DNA-templated chemistry.

Abstract:
Using a strand exchange mechanism we have prepared, by DNA templated chemistry, two 10-mers with defined and tunable monomer sequences. An optimized reaction protocol achieves 85% coupling yield per step, demonstrating that DNA-templated chemistry is a powerful tool for the synthesis of macromolecules with full sequence control.
Publication status:
Published

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Publisher copy:
10.1039/c2cc31975f

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Institution:
University of Oxford
Division:
MPLS
Department:
Physics
Role:
Author
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Journal:
Chemical Communications
Volume:
48
Issue:
45
Pages:
5614-5616
Publication date:
2012-06-01
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
Source identifiers:
328995
Language:
English
Keywords:
Pubs id:
pubs:328995
UUID:
uuid:a0783ebd-ea90-445e-9679-a754a1998b84
Local pid:
pubs:328995
Deposit date:
2012-12-19

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