Journal article
Dearomative photocatalytic construction of bridged 1,3-diazepanes
- Abstract:
-
The construction of diverse sp3 -rich skeletal ring systems is of importance to drug discovery programmes and natural product synthesis. Herein, we report the photocatalytic construction of 2,7-diazabicyclo[3.2.1]octanes (bridged 1,3-diazepanes) via a reductive diversion of the Minisci reaction. The fused tricyclic product is proposed to form via radical addition to the C4 position of 4-substituted quinoline substrates, with subsequent Hantzsch ester-promoted reduction to a dihydropyridine in...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
-
(Accepted manuscript, pdf, 2.3MB)
-
(Supplementary materials, pdf, 28.6MB)
-
- Publisher copy:
- 10.1002/anie.201914390
Authors
Funding
Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Angewandte Chemie International Edition Journal website
- Volume:
- 59
- Issue:
- 10
- Pages:
- 4121-4130
- Publication date:
- 2020-01-27
- Acceptance date:
- 2019-12-04
- DOI:
- EISSN:
-
1521-3773
- ISSN:
-
1433-7851
- Pmid:
-
31914213
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1084037
- Local pid:
- pubs:1084037
- Deposit date:
- 2020-04-14
Terms of use
- Copyright holder:
- Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim
- Copyright date:
- 2020
- Rights statement:
- © 2020 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Wiley at https://doi.org/10.1002/anie.201914390
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