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Journal article

Transposition-driven genomic heterogeneity in the Drosophila brain.

Abstract:

Recent studies in mammals have documented the neural expression and mobility of retrotransposons and have suggested that neural genomes are diverse mosaics. We found that transposition occurs among memory-relevant neurons in the Drosophila brain. Cell type-specific gene expression profiling revealed that transposon expression is more abundant in mushroom body (MB) αβ neurons than in neighboring MB neurons. The Piwi-interacting RNA (piRNA) proteins Aubergine and Argonaute 3, known to suppress ...

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Publication status:
Published

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Publisher copy:
10.1126/science.1231965

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
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Journal:
Science (New York, N.Y.)
Volume:
340
Issue:
6128
Pages:
91-95
Publication date:
2013-04-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:a05aa96e-e578-4459-876a-91406c7e59f0
Source identifiers:
395027
Local pid:
pubs:395027

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