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The role of skin-homing T cells in extrinsic atopic dermatitis.

Abstract:

BACKGROUND: T cells that express Cutaneous Lymphocyte-Associated antigen (CLA) have the potential of migrating to the skin, and are hypothesized to play a role in cutaneous atopic disease. AIM: To investigate the immune phenotype and cytokine responses to Der p 1 stimulation of CLA+ T cells in extrinsic atopic dermatitis (EAD). DESIGN: In vitro testing, with controls. METHODS: Peripheral blood mononuclear cells (PBMC) were obtained from EAD patients (n=27) and non-atopic healthy individuals (...

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Publication status:
Published

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Publisher copy:
10.1093/qjmed/hcl132

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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-CTU
Role:
Author
Journal:
QJM : monthly journal of the Association of Physicians
Volume:
100
Issue:
1
Pages:
19-27
Publication date:
2007-01-05
DOI:
EISSN:
1460-2393
ISSN:
1460-2725
URN:
uuid:a05a75f3-b00a-4acf-b15c-248b5b1854b4
Source identifiers:
19716
Local pid:
pubs:19716

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