Delayed initiation of subcutaneous insulin therapy after failure of oral glucose-lowering agents in patients with Type 2 diabetes: a population-based analysis in the UK.

Journal article

AIMS: The aim of this retrospective cohort study was to estimate the time to insulin initiation in patients with Type 2 diabetes inadequately controlled on oral glucose-lowering agents (OGLAs). METHODS: Insulin-naïve patients failing on OGLAs were identified from The Health Improvement Network database, which collects records from general practices throughout the UK. Patients were included if they were aged > or = 40 years, had concomitant prescriptions for > or = 2 OGLAs, and > or =...

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Authors: Rubino, A; McQuay, L; Gough, S; Kvasz, M; Tennis, P

• Publication status: Published
• Journal: Diabetic medicine : a journal of the British Diabetic Association
• Volume: 24
• Issue: 12
• Pages: 1412-1418
• Publication date: 2007-12-01
• DOI: 10.1111/j.1464-5491.2007.02279.x
• EISSN: 1464-5491
• ISSN: 0742-3071
• Language: English
• Keywords: Treatment Failure; Diabetes Mellitus, Type 2; Male; Insulin; Great Britain; Female; Middle Aged; Time Factors; Administration, Oral; Hypoglycemic Agents; Adult; Humans; Cohort Studies; Aged, 80 and over; Injections, Subcutaneous; Aged