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Journal article

Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice.

Abstract:

Lymphocytic choriomeningitis virus (LCMV), strain WE, is a non-cytopathic RNA virus that is highly adapted to its natural host, the mouse. Acute infection of adult mice leads to generalized virus spread, followed by cytotoxic T lymphocyte-mediated virus clearance below the detection levels of conventional assays within 2-3 weeks. Indirect evidence had suggested that virus or viral antigen might persist in the immune mouse. Here we demonstrate LCMV-WE persistence at low levels after infection ...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.96.21.11964

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division, Biomedical Research Centre
Role:
Author
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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
96
Issue:
21
Pages:
11964-11969
Publication date:
1999-10-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:a013cdad-735f-49b3-945a-d33ef136102e
Source identifiers:
30755
Local pid:
pubs:30755

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