Journal article icon

Journal article

Genetics and the general physician: insights, applications and future challenges.

Abstract:

Scientific and technological advances in our understanding of the nature and consequences of human genetic variation are now allowing genetic determinants of susceptibility to common multifactorial diseases to be defined, as well as our individual response to therapy. I review how genome-wide association studies are robustly identifying new disease susceptibility loci, providing insights into disease pathogenesis and potential targets for drug therapy. Some of the remarkable advances being ma...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1093/qjmed/hcp115

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
More from this funder
Funding agency for:
Knight, J
Grant:
074318
Publisher:
Oxford University Press Publisher's website
Journal:
QJM : monthly journal of the Association of Physicians Journal website
Volume:
102
Issue:
11
Pages:
757-772
Publication date:
2009-11-01
DOI:
EISSN:
1460-2393
ISSN:
1460-2725
Source identifiers:
3001
Language:
English
Keywords:
UUID:
uuid:a00e5ad0-01dd-4283-b4c0-7bea50b47dc8
Local pid:
pubs:3001
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP