- Abstract:
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Scientific and technological advances in our understanding of the nature and consequences of human genetic variation are now allowing genetic determinants of susceptibility to common multifactorial diseases to be defined, as well as our individual response to therapy. I review how genome-wide association studies are robustly identifying new disease susceptibility loci, providing insights into disease pathogenesis and potential targets for drug therapy. Some of the remarkable advances being ma...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 328.3KB)
-
- Publisher copy:
- 10.1093/qjmed/hcp115
-
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- Publisher:
- Oxford University Press Publisher's website
- Journal:
- QJM : monthly journal of the Association of Physicians Journal website
- Volume:
- 102
- Issue:
- 11
- Pages:
- 757-772
- Publication date:
- 2009-11-05
- DOI:
- EISSN:
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1460-2393
- ISSN:
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1460-2725
- URN:
-
uuid:a00e5ad0-01dd-4283-b4c0-7bea50b47dc8
- Source identifiers:
-
3001
- Local pid:
- pubs:3001
- Copyright holder:
- Knight J.C.
- Copyright date:
- 2009
- Notes:
- © 2009 Knight J.C. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Genetics and the general physician: insights, applications and future challenges.
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