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Journal article

Paraoxonase 2 (PON2) polymorphisms and development of renal dysfunction in type 2 diabetes: UKPDS 76.

Abstract:

AIMS/HYPOTHESIS: Identification of variants predicting development of renal dysfunction would offer substantial clinical benefits. There is evidence that coding non-synonymous variants in the gene encoding paraoxonase 2 (PON2) are associated with nephropathy in both type 1 and type 2 diabetes. METHODS: We examined the relationship between variation at the C311S and A148G polymorphisms (together with PON2 intronic variant rs12704795) and indices of renal dysfunction (progression to micro- and ...

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Publication status:
Published

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Publisher copy:
10.1007/s00125-006-0436-8

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Journal:
Diabetologia
Volume:
49
Issue:
12
Pages:
2892-2899
Publication date:
2006-12-05
DOI:
EISSN:
1432-0428
ISSN:
0012-186X
URN:
uuid:a00c1393-c216-44c2-8d39-b89988b15cd6
Source identifiers:
2365
Local pid:
pubs:2365

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