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Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): An abridged explanation and elaboration

Abstract:
The Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK) were developed to address widespread deficiencies in the reporting of such studies. The REMARK checklist consists of 20 items to report for published tumor marker prognostic studies. A detailed paper was published explaining the rationale behind checklist items, providing positive examples and giving empirical evidence of the quality of reporting. REMARK provides a comprehensive overview to educate on good reporting and provide a valuable reference for the many issues to consider when designing, conducting, and analyzing tumor marker studies and prognostic studies in medicine in general. Despite support for REMARK from major cancer journals, prognostic factor research studies remain poorly reported. To encourage dissemination and uptake of REMARK, we have produced this considerably abridged version of the detailed explanatory manuscript, which may also serve as a brief guide to key issues for investigators planning tumor marker prognostic studies. To summarize the current situation, more recent papers investigating the quality of reporting and related reporting guidelines are cited, but otherwise the literature is not updated. Another important impetus for this paper is that it serves as a basis for literal translations into other languages. Translations will help to bring key information to a larger audience world-wide. Many more details can be found in the original paper.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/jnci/djy088

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Centre for Statistics in Medicine
Role:
Author
ORCID:
0000-0002-7183-4083


More from this funder
Funding agency for:
Altman, DG
Grant:
C5529


Publisher:
Oxford University Press
Journal:
Journal of the National Cancer Institute More from this journal
Volume:
110
Issue:
8
Pages:
803-811
Publication date:
2018-06-04
Acceptance date:
2018-04-17
DOI:
EISSN:
1460-2105
ISSN:
0027-8874
Pmid:
29873743


Language:
English
Keywords:
Pubs id:
pubs:856972
UUID:
uuid:9fe22ebc-f7bc-4de3-a260-df17915b88b5
Local pid:
pubs:856972
Source identifiers:
856972
Deposit date:
2018-10-08

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