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Endemic dengue associated with the co-circulation of multiple viral lineages and localized density-dependent transmission.

Abstract:

Dengue is one of the most important infectious diseases of humans and has spread throughout much of the tropical and subtropical world. Despite this widespread dispersal, the determinants of dengue transmission in endemic populations are not well understood, although essential for virus control. To address this issue we performed a phylogeographic analysis of 751 complete genome sequences of dengue 1 virus (DENV-1) sampled from both rural (Dong Thap) and urban (Ho Chi Minh City) populations i...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.ppat.1002064

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Institution:
University of Oxford
Role:
Author
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Funding agency for:
Simmons, CP
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS pathogens Journal website
Volume:
7
Issue:
6
Pages:
e1002064
Publication date:
2011-06-05
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
URN:
uuid:9fc64445-efb0-4096-bd44-9d2e55fede53
Source identifiers:
166584
Local pid:
pubs:166584

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