Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic
- Genome editing using clustered regularly interspersed short palindromic repeats (CRISPR) and CRISPR-associated proteins offers the potential to facilitate safe and effective treatment of genetic diseases refractory to other types of intervention. Here, we identify some of the major challenges for clinicians, regulators, and human research ethics committees in the clinical translation of CRISPR-mediated somatic cell therapy.
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- Genome medicine Journal website
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- Nicol et al.
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© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0
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