Journal article icon

Journal article

Temperature triggers immune evasion by Neisseria meningitidis

Abstract:

Neisseria meningitidis has several strategies to evade complement-mediated killing, and these contribute to its ability to cause septicaemic disease and meningitis. However, the meningococcus is primarily an obligate commensal of the human nasopharynx, and it is unclear why the bacterium has evolved exquisite mechanisms to avoid host immunity. Here we demonstrate that mechanisms of meningococcal immune evasion and resistance against complement increase in response to an increase in ambient te...

Expand abstract

Actions


Access Document


Publisher copy:
10.1038/nature12616

Authors


Expand authors...
Journal:
Nature
Volume:
502
Issue:
7470
Pages:
237-240
Publication date:
2013-01-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:9fba7158-f934-484d-aea2-4cac1442db9a
Source identifiers:
436399
Local pid:
pubs:436399
Language:
English

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP