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Agomelatine efficacy and acceptability revisited: systematic review and meta-analysis of published and unpublished randomised trials.

Abstract:

BACKGROUND: Agomelatine is a novel antidepressant drug with narrative, non-systematic reviews making claims of efficacy. AIMS: The present study systematically reviewed published and unpublished evidence of the acute and long-term efficacy and acceptability of agomelatine compared with placebo in the treatment of major depression. METHOD: Randomised controlled trials comparing agomelatine with placebo in the treatment of unipolar major depression were systematically reviewed. Primary outcomes...

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Publication status:
Published

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Publisher copy:
10.1192/bjp.bp.112.120196

Authors


Koesters, M More by this author
Guaiana, G More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Journal:
The British journal of psychiatry : the journal of mental science
Volume:
203
Issue:
3
Pages:
179-187
Publication date:
2013-09-05
DOI:
EISSN:
1472-1465
ISSN:
0007-1250
URN:
uuid:9fb59745-110d-457a-8b50-170099f5fc02
Source identifiers:
453526
Local pid:
pubs:453526

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