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Evaluating saliva sampling with reverse transcription loop-mediated isothermal amplification to improve access to SARS-CoV-2 diagnosis in low-resource settings

Abstract:

Standard diagnosis of SARS-CoV-2 by nasopharyngeal swab (NPS) and real-time reverse transcriptase-polymerase chain reaction (PCR) requires a sophisticated laboratory, skilled staff, and expensive reagents that are difficult to establish and maintain in isolated, low-resource settings. In the remote setting of tropical Sumba Island, eastern Indonesia, we evaluated alternative sampling with fresh saliva (FS) and testing with colorimetric loop-medicated isothermal amplification (LAMP). Between A...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.4269/ajtmh.22-0230

Authors


Publisher:
American Society of Tropical Medicine and Hygiene
Journal:
American Journal of Tropical Medicine and Hygiene More from this journal
Volume:
107
Issue:
2
Pages:
284-290
Publication date:
2022-07-05
Acceptance date:
2022-04-21
DOI:
EISSN:
1476-1645
ISSN:
0002-9637
Pmid:
35895405
Language:
English
Keywords:
Pubs id:
1270262
Local pid:
pubs:1270262
Deposit date:
2022-11-08

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