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Expression of complement regulatory proteins on islets of Langerhans: a comparison between human islets and islets isolated from normal and hDAF transgenic pigs.

Abstract:

BACKGROUND: The expression of regulators of complement activity (RCAs) on islet cells may be of great importance for protecting them against complement-mediated lysis in the immediate posttransplant period after intraportal islet transplantation. We examined porcine and human islet cells for expression of RCA. We also examined to what extent human decay accelerating factor (hDAF) is expressed on adult and fetal islet cells isolated from hDAF transgenic (TG) pigs having a high transgene expres...

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Publisher copy:
10.1097/00007890-200107270-00026

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Journal:
Transplantation More from this journal
Volume:
72
Issue:
2
Pages:
312-319
Publication date:
2001-07-01
DOI:
EISSN:
1534-6080
ISSN:
0041-1337

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