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Journal article

Head and neck cancer relapse after chemoradiotherapy correlates with CD163+ macrophages in primary tumour and CD11b+ myeloid cells in recurrences.

Abstract:

BACKGROUND: We investigated the prognostic role of tumour-associated macrophages (TAMs) in patients with head and neck squamous cell carcinoma (HNSCC) treated with definitive chemoradiotherapy (CRT). METHODS: The expression of CD68+, CD163+ and CD11b+ cells was assessed using immunohistochemistry in n=106 pre-treatment tumour biopsy samples and was correlated with clinicopathological characteristics, including T-stage, N-stage, grading, tumour localisation, age and sex as well as local failur...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/bjc.2014.446

Authors


Balermpas, P More by this author
Oppermann, J More by this author
Wagenblast, J More by this author
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Publisher:
Cancer Research UK Publisher's website
Journal:
British journal of cancer Journal website
Volume:
111
Issue:
8
Pages:
1509-1518
Publication date:
2014-10-05
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
URN:
uuid:9fa71eda-414f-4057-8c25-5865cffd7ae2
Source identifiers:
479830
Local pid:
pubs:479830

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