Journal article icon

Journal article

Generation of immunogenic dendritic cells from human embryonic stem cells without serum and feeder cells.

Abstract:

AIM: Dendritic cell (DC)-based vaccines have a potential utility for use in the treatment of malignancy. Human embryonic stem cells (hESCs) may provide a more cost-effective and reliable source of DCs for immunotherapy purposes, providing on-demand access for patients. METHOD: We developed a protocol to generate DCs from hESCs in vitro in the absence of serum and feeder cells. This protocol uses growth factors bone morphogenetic protein-4, granulocyte macrophage-colony stimulating factor (GM-...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.2217/rme.09.25

Authors


Nishimoto, KP More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Majumdar, AS More by this author
Expand authors...
Journal:
Regenerative medicine
Volume:
4
Issue:
4
Pages:
513-526
Publication date:
2009-07-05
DOI:
EISSN:
1746-076X
ISSN:
1746-0751
URN:
uuid:9f5cca50-4d72-4bd6-848d-0af40dc9104e
Source identifiers:
28236
Local pid:
pubs:28236

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP