Journal article
A high-resolution melt curve toolkit to identify lineage-defining SARS-CoV-2 mutations
- Abstract:
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The emergence of severe acute respiratory syndrome 2 (SARS-CoV-2) variants of concern (VOCs), with mutations linked to increased transmissibility, vaccine escape and virulence, has necessitated the widespread genomic surveillance of SARS-CoV-2. This has placed a strain on global sequencing capacity, especially in areas lacking the resources for large scale sequencing activities. Here we have developed three separate multiplex high-resolution melting assays to enable the identification of Alph...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 1.6MB, Terms of use)
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- Publisher copy:
- 10.1038/s41598-023-30754-1
Authors
Funding
Bibliographic Details
- Publisher:
- Springer Nature
- Journal:
- Scientific Reports More from this journal
- Volume:
- 13
- Issue:
- 1
- Article number:
- 3887
- Place of publication:
- England
- Publication date:
- 2023-03-08
- Acceptance date:
- 2023-02-28
- DOI:
- EISSN:
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2045-2322
- ISSN:
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2045-2322
- Pmid:
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36890186
Item Description
- Language:
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English
- Pubs id:
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1335864
- Local pid:
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pubs:1335864
- Deposit date:
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2024-04-16
Terms of use
- Copyright holder:
- Fraser et al
- Copyright date:
- 2023
- Rights statement:
- © 2023, The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
- Licence:
- CC Attribution (CC BY)
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