Journal article icon

Journal article

Phorbol ester-induced expression and function of the interleukin 2 receptor in human B lymphocytes.

Abstract:

The expression of the interleukin 2 receptor (Tac) on normal B cells and Epstein-Barr virus-transformed lymphoblastoid B cell lines is induced by the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate (TPA). The receptor on B cells is indistinguishable from that on T cells by serological and biochemical analysis. It is functionally active so that TPA-induced B cells respond to interleukin 2 by increased DNA synthesis. These results suggest that the expression of Tac is not exclusively restr...

Expand abstract

Actions


Access Document


Publisher copy:
10.1002/eji.1830150407

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
European journal of immunology
Volume:
15
Issue:
4
Pages:
341-344
Publication date:
1985-04-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:9f32fef4-f1f3-4f49-8cff-dcf71cf25c2c
Source identifiers:
35282
Local pid:
pubs:35282

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP