Conference icon

Conference

Muscarine-gated K+ channel: subunit stoichiometry and structural domains essential for G protein stimulation.

Abstract:

Coexpression in Xenopus oocytes of the cloned cardiac inward rectifier subunits Kir 3.1 and Kir 3.4 results in G protein-stimulated channel activity closely resembling the muscarinic channel underlying the inwardly rectifying K+ current in atrial myocytes. To determine the stoichiometry and relative subunit positions within the channel, Kir 3.1 and Kir 3.4 were coexpressed in varying ratios with cloned G beta 1 gamma 2 subunits and also as tandemly linked tetramers with different relative sub...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Physics, Condensed Matter Physics
Adelman, JP More by this author
Volume:
271
Issue:
1 Pt 2
Pages:
H379-H385
Publication date:
1996-07-05
ISSN:
0002-9513
URN:
uuid:9f2dd627-7c56-491e-b4f2-a0e67f05bcd9
Source identifiers:
26363
Local pid:
pubs:26363

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP