- Abstract:
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Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a genome-wide association study for whole body (20 cohorts of European ancestry with n = 38,292) and appendicular (arms and legs) lean body mass (n = 28,330) measured using dual energy X-ray absorptiometry or bioelectrical impedance analysis, adjusted for sex, age, height, and fat mass. Twenty-one single-nucleotide polymorphisms were significantly associated with lean body mass either genome wid...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 352.9KB)
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(pdf, 190.3KB)
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- Publisher copy:
- 10.1038/s41467-017-00031-7
-
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- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Communications Journal website
- Volume:
- 8
- Issue:
- 1
- Pages:
- Article: 80
- Publication date:
- 2017-07-19
- Acceptance date:
- 2017-05-02
- DOI:
- ISSN:
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2041-1723
- Pubs id:
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pubs:709089
- URN:
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uri:9f005915-4507-4123-8b3e-99a8c3b6a659
- UUID:
-
uuid:9f005915-4507-4123-8b3e-99a8c3b6a659
- Local pid:
- pubs:709089
- Language:
- English
- Copyright holder:
- Zillikens et al.
- Copyright date:
- 2017
- Notes:
-
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Note: an erratum exists for this article, originally published and available at: https://doi.org/10.1038/s41467-017-01008-2
Journal article
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
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