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The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast

Abstract:
The kinetochore is the macromolecular protein complex that mediates chromosome segregation. The Dsn1 component is crucial for kinetochore assembly and is phosphorylated by the Aurora B kinase. We found that Aurora B phosphorylation of Dsn1 promotes the interaction between outer and inner kinetochore proteins in budding yeast. © 2013 by the Genetics Society of America.

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Nelson, CR More by this author
Biggins, S More by this author
Journal:
Genetics
Volume:
194
Issue:
3
Pages:
785-789
Publication date:
2013-07-05
DOI:
EISSN:
1943-2631
ISSN:
0016-6731
URN:
uuid:9efd467c-7cb4-4574-91dc-950fb9456ff0
Source identifiers:
412080
Local pid:
pubs:412080
Language:
English

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