- The kinetochore is the macromolecular protein complex that mediates chromosome segregation. The Dsn1 component is crucial for kinetochore assembly and is phosphorylated by the Aurora B kinase. We found that Aurora B phosphorylation of Dsn1 promotes the interaction between outer and inner kinetochore proteins in budding yeast. © 2013 by the Genetics Society of America.
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The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast
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