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Journal article

Familial and phenotypic associations of the aldosterone Renin ratio.

Abstract:

CONTEXT: The aldosterone to renin ratio (ARR) is a marker of aldosterone excess, widely used to screen for primary aldosteronism (PA). The significance of a raised ARR in normotensive and hypertensive subjects and the phenotypic and familial factors affecting it are unclear. OBJECTIVE: We estimated the distribution and heritability of the ARR and tested for associations between ARR and blood pressure (BP) with 11 polymorphisms at the CYP11B1/CYP11B2 locus. DESIGN AND SETTING: A total of 1172 ...

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Publication status:
Published

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Publisher copy:
10.1210/jc.2009-1406

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Journal:
The Journal of clinical endocrinology and metabolism
Volume:
94
Issue:
11
Pages:
4324-4333
Publication date:
2009-11-05
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
URN:
uuid:9ee6740d-a5bd-4102-8ad6-0e9e5ad2101b
Source identifiers:
104334
Local pid:
pubs:104334

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