Journal article icon

Journal article

Evaluation of a human T cell-targed multi-epitope vaccine for Q fever in animal models of Coxiella burnetii immunity

Abstract:

T cell-mediated immunity plays a central role in the control and clearance of intracellular Coxiella burnetii infection, which can cause Q fever. Therefore, we aimed to develop a novel T cell-targeted vaccine that induces pathogen-specific cell-mediated immunity to protect against Q fever in humans while avoiding the reactogenicity of the current inactivated whole cell vaccine. Human HLA class II T cell epitopes from C. burnetii were previously identified and selected by immunoinformatic pred...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.3389/fimmu.2022.901372

Authors


Expand authors...
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Immunology Journal website
Volume:
13
Article number:
901372
Publication date:
2022-05-16
Acceptance date:
2022-04-20
DOI:
EISSN:
1664-3224
Pmid:
35651616
Language:
English
Keywords:
Pubs id:
1264093
Local pid:
pubs:1264093
Deposit date:
2022-07-21

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP