Lessons we can learn from gene expression patterns in rotator cuff tears and tendinopathies.

Journal article

Persistently high failure rates that are reported after rotator cuff repairs have encouraged greater understanding of the pathophysiology that underlies rotator cuff tears. Biologic changes that contribute to the pathogenesis of rotator cuff tears and tendinopathies, as well as adaptation after these changes, have been well described. A subset of patients with a genetic predisposition to early onset of rotator cuff tears and earlier symptom and disease progression have been identified. Many b...

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Authors: Chaudhury, S; Carr, A

• Publication status: Published
• Journal: Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.]
• Volume: 21
• Issue: 2
• Pages: 191-199
• Publication date: 2012-02-01
• DOI: 10.1016/j.jse.2011.10.022
• EISSN: 1532-6500
• ISSN: 1058-2746
• Language: English
• Keywords: Rotator Cuff; Tendon Injuries; Extracellular Matrix; Needs Assessment; Tendinopathy; Humans; Gene Expression Regulation; Wound Healing; Genetic Predisposition to Disease; Risk Assessment