Journal article
The T309G MDM2 gene polymorphism is a novel risk factor for proliferative vitreoretinopathy.
- Abstract:
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Proliferative vitreoretinopathy (PVR) is still the major cause of failure in retinal detachment (RD) surgery. It is believed that down-regulation in the p53 pathway could be an important key in PVR pathogenesis. The purpose was to evaluate the impact of T309G MDM2 polymorphism (rs2279744) in PVR. Distribution of T309G MDM2 genotypes among European subjects undergoing RD surgery was evaluated. Proportions of genotypes between subsamples from different countries were analyzed. Also, a genetic i...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 531.3KB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0082283
Authors
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PLoS ONE More from this journal
- Volume:
- 8
- Issue:
- 12
- Pages:
- e82283
- Publication date:
- 2013-12-09
- Acceptance date:
- 2013-10-31
- DOI:
- EISSN:
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1932-6203
Item Description
- Language:
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English
- Keywords:
-
- UUID:
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uuid:9eac708b-ce23-46a8-b7d1-3b469f0cd795
- Local pid:
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pubs:444430
- Source identifiers:
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444430
- Deposit date:
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2014-02-13
Terms of use
- Copyright holder:
- Pastor-Idoate et al
- Copyright date:
- 2013
- Notes:
- © 2013 Pastor-Idoate et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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