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Journal article

Platelet activating factor contributes to vascular leak in acute dengue infection.

Abstract:

Background

Although plasma leakage is the hallmark of severe dengue infections, the factors that cause increased vascular permeability have not been identified. As platelet activating factor (PAF) is associated with an increase in vascular permeability in other diseases, we set out to investigate its role in acute dengue infection.

Materials and Methods

PAF levels were initially assessed in 25 patients with acute dengue infection to determine if they were increased...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pntd.0003459

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM - Investigative Medicine Division
Role:
Author
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Centre for Dengue Research More from this funder
Medical Research Council More from this funder
Commonwealth Commission More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Neglected Tropical Diseases Journal website
Volume:
9
Issue:
2
Pages:
e0003459
Chapter number:
ARTN e0003459
Publication date:
2015-02-05
DOI:
EISSN:
1935-2735
ISSN:
1935-2727
URN:
uuid:9e679be4-73af-4a27-9e8b-5c1d14b5404b
Source identifiers:
506794
Local pid:
pubs:506794

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