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Journal article

An investigation of the expression of G1-phase cell cycle proteins in focal cortical dysplasia type IIB.

Abstract:

Balloon cells (BCs) are the pathologic hallmark of focal cortical dysplasia type IIB, a common cause of pharmacoresistent epilepsy. Expression of markers of cell immaturity and of the proliferation marker minichromosome maintenance protein 2 (mcm2) have been previously shown in BCs, suggesting that these cells might represent a pool of less-differentiated cells licensed for replication. An alternative explanation is that these cells are the remnants of early cortical plate cells that have fai...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
Journal of neuropathology and experimental neurology
Volume:
66
Issue:
11
Pages:
1045-1055
Publication date:
2007-11-05
DOI:
EISSN:
1554-6578
ISSN:
0022-3069
URN:
uuid:9e640d2b-f03b-454b-b998-5c5ff95519f5
Source identifiers:
456222
Local pid:
pubs:456222

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