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Journal article

The developmental origin of heart size and shape differences in Astyanax mexicanus populations

Abstract:

Regulation of heart size and shape is one of the least understood processes in developmental biology. We have for the first time analysed the hearts of Astyanax mexicanus and identified several differences in heart morphology between the surface (epigean morph) and cave-dwelling (troglomorph) morphs. Examination of the adult revealed that the troglomorph possesses a smaller heart with a rounder ventricle in comparison to the epigean morph. The size differences identified appear to arise early...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ydbio.2018.06.009

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
Publisher:
Elsevier
Journal:
Developmental Biology More from this journal
Volume:
441
Issue:
2
Pages:
272-284
Publication date:
2018-06-22
Acceptance date:
2018-06-13
DOI:
EISSN:
1095-564X
ISSN:
0012-1606
Language:
English
Keywords:
Pubs id:
pubs:859452
UUID:
uuid:9e5d198b-7a84-4c15-a1b9-ddab5d133b01
Local pid:
pubs:859452
Deposit date:
2018-06-26

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