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Journal article

Non-viral nanovectors for gene delivery: factors that govern successful therapeutics.

Abstract:

IMPORTANCE OF THE FIELD: Gene therapy is regarded as one of the most promising therapeutic approaches, as it has the potential to treat disorders by correcting malformations at the nucleic acids. AREAS COVERED IN THIS REVIEW: Some of the most recent developments in the process of plasmid DNA vector design and formulation are reviewed with a special focus on: different formulations of nanovectors and a summary of successful cases reported; requirements for systemic administration; and functio...

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Publication status:
Published

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Publisher copy:
10.1517/17425241003716810

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Expert opinion on drug delivery
Volume:
7
Issue:
6
Pages:
721-735
Publication date:
2010-06-01
DOI:
EISSN:
1744-7593
ISSN:
1742-5247
Source identifiers:
263284
Language:
English
Keywords:
Pubs id:
pubs:263284
UUID:
uuid:9e50be87-f652-4017-882e-5d25970e8c19
Local pid:
pubs:263284
Deposit date:
2012-12-19

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