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Journal article

Non-viral nanovectors for gene delivery: factors that govern successful therapeutics.

Abstract:

IMPORTANCE OF THE FIELD: Gene therapy is regarded as one of the most promising therapeutic approaches, as it has the potential to treat disorders by correcting malformations at the nucleic acids. AREAS COVERED IN THIS REVIEW: Some of the most recent developments in the process of plasmid DNA vector design and formulation are reviewed with a special focus on: different formulations of nanovectors and a summary of successful cases reported; requirements for systemic administration; and functio...

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Publication status:
Published

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Publisher copy:
10.1517/17425241003716810

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Journal:
Expert opinion on drug delivery
Volume:
7
Issue:
6
Pages:
721-735
Publication date:
2010-06-05
DOI:
EISSN:
1744-7593
ISSN:
1742-5247
URN:
uuid:9e50be87-f652-4017-882e-5d25970e8c19
Source identifiers:
263284
Local pid:
pubs:263284

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