Journal article
Association and haplotype analysis of the insulin-degrading enzyme (IDE) gene, a strong positional and biological candidate for type 2 diabetes susceptibility.
- Abstract:
-
The gene for insulin-degrading enzyme (IDE) represents a strong positional and biological candidate for type 2 diabetes susceptibility. IDE maps to chromosome 10q23.3, a region linked to diabetes in several populations; the rat homolog has been directly implicated in diabetes susceptibility; and known functions of IDE support an important role in glucose homeostasis. We sought evidence for association between IDE variation and diabetes by mutation screening, defining local haplotype structure...
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- Publication status:
- Published
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- Publisher copy:
- 10.2337/diabetes.52.5.1300
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Authors
Bibliographic Details
- Journal:
- Diabetes
- Volume:
- 52
- Issue:
- 5
- Pages:
- 1300-1305
- Publication date:
- 2003-05-01
- DOI:
- EISSN:
-
1939-327X
- ISSN:
-
0012-1797
- Source identifiers:
-
3982
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:3982
- UUID:
-
uuid:9e46ed9f-5f35-4d5f-8fa8-94efd1ef917a
- Local pid:
- pubs:3982
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2003
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