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Thesis

Hypoxia and HIF signalling in the epicardium during development and regeneration

Abstract:

Heart failure is a major cause of death worldwide due to the inability of the mammalian heart to regenerate after injury. The neonatal mouse heart however mounts a substantial regenerative response; though this capacity is lost one week after birth. The epicardium, which is activated in response to injury, becomes quiescent during this time-frame and may, therefore, be involved in the loss of regenerative potential. Another key change that occurs in the heart after birth is the transition...

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Eleanor Price More by this author

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Department:
Paul Riley
Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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