Journal article
Glycoprotein synthesis: From glycobiological tools to tailor-made catalysts
- Abstract:
- The synthesis of pure, well-defined glycoproteins is essential to the study of the host of biological processes that they mediate. The use of a combined site-directed mutagenesis and chemical modification strategy allows the site-selective synthesis of homogenous glycoproteins, the determination of precise structure-activity relationships and the design of new synthetic catalysts. This general and powerful method is reviewed in the context of existing preparative techniques and the wide-ranging applications of glycoproteins are highlighted.
- Publication status:
- Published
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Authors
- Publisher:
- Georg Thieme Verlag
- Journal:
- SYNLETT More from this journal
- Volume:
- 1999
- Issue:
- 9
- Pages:
- 1495-1507
- Publication date:
- 1999-09-01
- DOI:
- EISSN:
-
1437-2096
- ISSN:
-
0936-5214
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:52105
- UUID:
-
uuid:9e0fbcff-8485-4c99-90e1-a7fa8c8f3b2e
- Local pid:
-
pubs:52105
- Source identifiers:
-
52105
- Deposit date:
-
2012-12-19
Terms of use
- Copyright date:
- 1999
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