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Changes in cerebral blood flow during and after 48 h of both isocapnic and poikilocapnic hypoxia in humans.

Abstract:

During acclimatization to the hypoxia of altitude, the cerebral circulation is exposed to arterial hypoxia and hypocapnia, two stimuli with opposing influences on cerebral blood flow (CBF). In order to understand the resultant changes in CBF, this study examined the responses of CBF during a period of constant mild hypoxia both with and without concomitant regulation of arterial P(CO2). Nine subjects were each exposed to two protocols in a purpose-built chamber: (1) 48 h of isocapnic hypoxia ...

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Publication status:
Published

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Publisher copy:
10.1113/eph8702437

Authors


Poulin, MJ More by this author
Fatemian, M More by this author
Tansley, JG More by this author
O'Connor, DF More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
Experimental physiology
Volume:
87
Issue:
5
Pages:
633-642
Publication date:
2002-09-05
DOI:
EISSN:
1469-445X
ISSN:
0958-0670
URN:
uuid:9dd33fb1-a7bd-43f6-ae64-34fb92ecb7a4
Source identifiers:
113771
Local pid:
pubs:113771

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