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Journal article

Macrophage-osteoclast differentiation and bone resorption in osteoarthrotic subchondral acetabular cysts.

Abstract:

A macrophage infiltrate is commonly found in enlarging subchondral cysts in osteoarthrosis (OA) and the surrounding bone. To determine whether osteoclast differentiation by these cells contributes to the increase in the number of osteoclasts and bone resorption that accompanies OA cyst enlargement, we isolated macrophages from the wall of OA cysts and co-cultured them with osteoblast-like UMR106 cells in the presence or absence of 1,25(OH)2D3 and M-CSE After 14 days of incubation, co-cultures...

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Publication status:
Published

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Publisher copy:
10.1080/000164700317411843

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
Acta orthopaedica Scandinavica
Volume:
71
Issue:
3
Pages:
255-261
Publication date:
2000-06-05
DOI:
EISSN:
1745-3682
ISSN:
0001-6470
URN:
uuid:9dc244e7-4b86-4b52-ba38-5697664b163d
Source identifiers:
62381
Local pid:
pubs:62381

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