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The short Synacthen (corticotropin) test can be used to predict recovery of hypothalamo-pituitary-adrenal axis function

Abstract:

The 250μg Short Synacthen (corticotropin) Test (SST) is the most commonly used tool to assess hypothalamo-pituitary-adrenal (HPA) axis function. There are many potentially reversible causes of adrenal insufficiency (AI), but currently no data to guide clinicians as to the frequency of repeat testing or likelihood of HPA axis recovery.To use the SST results to predict recovery of adrenal function.A retrospective analysis of data from 1912 SSTs.776 patients with reversible causes of AI were ide...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1210/jc.2018-00529

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; OCDEM
Feliciano, C More by this author
Sbardella, E More by this author
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Funding agency for:
Pofi, R
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Funding agency for:
Tomlinson, JW
Publisher:
Oxford University Press Publisher's website
Journal:
Journal of Clinical Endocrinology and Metabolism Journal website
Volume:
103
Issue:
8
Pages:
3050–3059
Publication date:
2018-05-25
Acceptance date:
2018-05-22
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
Pubs id:
pubs:854632
URN:
uri:9da42fdb-bbca-46c4-949a-529d88170dae
UUID:
uuid:9da42fdb-bbca-46c4-949a-529d88170dae
Local pid:
pubs:854632
Language:
English
Keywords:

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