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Virus morphogenesis and viral entry as alternative targets for novel hepatitis C antivirals

Abstract:

Hepatitis C virus (HCV) infection is a major public health concern. New antiviral drugs are required urgently to complement and improve the efficacy of current chemotherapies. Molecules specifically targeting viral enzymes are the most attractive in terms of drug development and are, therefore, the most studied. However, an antiviral strategy based uniquely on the utilization of this type of target is expected to encounter problems caused by the emergence of viral escape mutants as has alread...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.2217/17460794.1.2.197

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Durantel, D More by this author
Publisher:
Future Medicine Publisher's website
Journal:
Future Virology Journal website
Volume:
1
Issue:
2
Pages:
197-209
Publication date:
2006-03-05
DOI:
EISSN:
1746-0808
ISSN:
1746-0794
URN:
uuid:9d8c9404-80aa-4240-a74e-cce68827dba6
Source identifiers:
100406
Local pid:
pubs:100406

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