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Virus morphogenesis and viral entry as alternative targets for novel hepatitis C antivirals

Abstract:

Hepatitis C virus (HCV) infection is a major public health concern. New antiviral drugs are required urgently to complement and improve the efficacy of current chemotherapies. Molecules specifically targeting viral enzymes are the most attractive in terms of drug development and are, therefore, the most studied. However, an antiviral strategy based uniquely on the utilization of this type of target is expected to encounter problems caused by the emergence of viral escape mutants as has alread...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.2217/17460794.1.2.197

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Publisher:
Future Medicine
Journal:
Future Virology More from this journal
Volume:
1
Issue:
2
Pages:
197-209
Publication date:
2006-03-01
DOI:
EISSN:
1746-0808
ISSN:
1746-0794
Keywords:
Pubs id:
pubs:100406
UUID:
uuid:9d8c9404-80aa-4240-a74e-cce68827dba6
Local pid:
pubs:100406
Source identifiers:
100406
Deposit date:
2012-12-19

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