- Abstract:
-
Mitotic index is an important component of histologic grade and has an etiologic role in breast tumorigenesis. Several small candidate gene studies have reported associations between variation in mitotic genes and breast cancer risk. We measured associations between 2156 single nucleotide polymorphisms (SNPs) from 194 mitotic genes and breast cancer risk, overall and by histologic grade, in the Breast Cancer Association Consortium (BCAC) iCOGS study (n = 39 067 cases; n = 42 106 controls). SN...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1093/hmg/ddu300
-
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- Journal:
- Human molecular genetics
- Volume:
- 23
- Issue:
- 22
- Pages:
- 6034-6046
- Publication date:
- 2014-11-05
- DOI:
- EISSN:
-
1460-2083
- ISSN:
-
0964-6906
- URN:
-
uuid:9d78c190-33a0-4218-b490-b83ad539ece3
- Source identifiers:
-
469516
- Local pid:
- pubs:469516
- Language:
- English
- Keywords:
- Copyright date:
- 2014
Journal article
Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.
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