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Co-modulation of finely tuned high-gamma band activity across hemispheres in Parkinson's disease.

Abstract:

OBJECTIVE: Dopaminergic treatment of patients with Parkinson's disease can be associated with a finely tuned high-gamma (FTG) band oscillation between 60 and 90 Hz in the basal ganglia (BG) nuclei. This activity, together with suppression of excessive neural synchrony in the beta frequency band (15-30 Hz), is hypothesized to contribute to the pro-kinetic effects of dopaminergic medication. Beta activity, which high-gamma replaces, has been shown to be bilaterally coherent, but whether sub-cor...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Molecular Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Journal:
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Volume:
125
Issue:
4
Pages:
777-785
Publication date:
2014-04-05
DOI:
EISSN:
1872-8952
ISSN:
1388-2457
URN:
uuid:9d42899f-dcf1-4ac5-b50c-10390b5cd243
Source identifiers:
436036
Local pid:
pubs:436036

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