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Thesis

MicroRNA expression and activity in high-grade serous ovarian cancer

Abstract:

miRNAs are critical modulators in the development and progression of cancer. Emerging evidence suggests that they are drivers of ovarian cancer. A better understanding of the molecular underpinnings of the development, progression and chemoresistance of the disease is critical for the development of new, more effective therapies. Here we explore the expression patterns of miRNAs as they relate to gene expression, as they differ across molecular subtypes of the disease.

We examine the ...

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Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Oxford college:
Kellogg College
Role:
Author

Contributors

Division:
MPLS
Department:
Statistics
Role:
Supervisor
Division:
MPLS
Department:
Statistics
Role:
Supervisor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:9d17590c-550b-4ae9-ac8d-15387cf70e5f
Local pid:
ora:7116
Deposit date:
2013-07-29

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