MicroRNA expression and activity in high-grade serous ovarian cancer
miRNAs are critical modulators in the development and progression of cancer. Emerging evidence suggests that they are drivers of ovarian cancer. A better understanding of the molecular underpinnings of the development, progression and chemoresistance of the disease is critical for the development of new, more eﬀective therapies. Here we explore the expression patterns of miRNAs as they relate to gene expression, as they diﬀer across molecular subtypes of the disease.
We examine the ...Expand abstract
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- Oxford University, UK
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- Eleanor A. Howe
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- This thesis is not currently available in ORA.
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