Thesis
MicroRNA expression and activity in high-grade serous ovarian cancer
- Abstract:
-
miRNAs are critical modulators in the development and progression of cancer. Emerging evidence suggests that they are drivers of ovarian cancer. A better understanding of the molecular underpinnings of the development, progression and chemoresistance of the disease is critical for the development of new, more effective therapies. Here we explore the expression patterns of miRNAs as they relate to gene expression, as they differ across molecular subtypes of the disease.
We examine the ...
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Authors
Contributors
+ Holmes, C
Division:
MPLS
Department:
Statistics
Role:
Supervisor
+ Quackenbush, J
Division:
MPLS
Department:
Statistics
Role:
Supervisor
Bibliographic Details
- Publication date:
- 2012
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:9d17590c-550b-4ae9-ac8d-15387cf70e5f
- Local pid:
- ora:7116
- Deposit date:
- 2013-07-29
Terms of use
- Copyright holder:
- Howe, E
- Copyright date:
- 2012
- Notes:
- This thesis is not currently available in ORA.
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